Effective Nanoparticle-Based Nasal Vaccine Against Latent and Congenital Toxoplasmosis in Sheep

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Latent Toxoplasmosis and Human

Toxoplasmosis is one of the most common parasitic diseases worldwide. Although estimated that one third of the world's population are infected with Toxoplasma gondii, but the most common form of the disease is latent (asymptomatic). On the other hand, recent findings indicated that latent toxoplasmosis is not only unsafe for human, but also may play various roles in the etiology of different me...

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Diclazuril Protects against Maternal Gastrointestinal Syndrome and Congenital Toxoplasmosis

BACKGROUND Toxoplasmosis is a common cause of foodborne, gastrointestinal and congenital syndrome with particularly severe or unknown health consequences. There is no safe and effective preventive or therapeutic modality against congenital toxoplasmosis or to eliminate the persistent chronic infection. HYPOTHESIS Diclazuril to be safe in pregnancy and effective against gastrointestinal toxopl...

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latent toxoplasmosis and human

toxoplasmosis is one of the most common parasitic diseases worldwide. although estimated that one third of the world's population are infected with toxoplasma gondii , but the most common form of the disease is latent (asymptomatic). on the other hand, recent findings indicated that la­tent toxoplasmosis is not only unsafe for human, but also may play various roles in the etiol­ogy of different...

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Congenital toxoplasmosis.

Congenital toxoplasmosis results from the transplacental transmission of the parasite Toxoplasma gondii after a maternal infection acquired in pregnancy. Prevalence of congenital infection ranges from 0.1 to 0.3 per 1000 live births. The maternal-fetal transmission rate increases with gestational age at maternal seroconversion, from less than 15% at 13 weeks of gestation to over 70% at 36 weeks...

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Congenital toxoplasmosis.

The history of toxoplasmosis began in 1923 with the F first published description of a human case, a congenitally infected baby. Toxoplasma gondii had been recognised 15 years earlier, but it was not until 1%96 that the life cycle of this protozoan parasite was understood, with the discovery that the definitive host : was any member of the cat family (fig 1).' 2 _ Despite extensive clinical and...

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ژورنال

عنوان ژورنال: Frontiers in Immunology

سال: 2020

ISSN: 1664-3224

DOI: 10.3389/fimmu.2020.02183